Skip to content

Assessing pain relief following dental implant surgery with 0.3% benzydamine hydrochloride spray: A double-blind, randomized clinical trial

The effectiveness of 0.3% Benzydamine Hydrochloride spray in controlling pain after dental implant surgery: An open-label, double -blind, randomized clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20240528003
Enrollment
30
Registered
2024-05-28
Start date
2020-01-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy participation (ASA I and II) aged 18 or over undergoing single posterior implant treatment Benzydamine, Dental implant, Pain measurement, Analgesics

Interventions

0.3% benzydamine hydrochloride was obtained from the manufacturing company.,The placebo used in the study was sourced from the same manufacturing company to guarantee uniformity in consistency, scent,
Active Comparator Drug,Placebo Comparator Drug
Benzydamine hydrochloride,Placebo

Sponsors

Intramural Research Fund, Faculty of Dentistry, Chulalongkorn University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with tooth loss for at least 3 months. Bone-level submerged implants were inserted under local anesthesia without premedication.

Exclusion criteria

Exclusion criteria: Smoking, allergy to BNZD and acetaminophen, regular use of medications affecting pain levels, need for bone or soft tissue augmentation, maxillary sinus augmentation, or pregnancy or lactation.

Design outcomes

Primary

MeasureTime frame
Pain 3, 6, 18, 24, 48 hours after surgery Visual analoque scale

Secondary

MeasureTime frame
Usage of spray 48 hours Times,Number of rescue analgesics 48 hours Number of pills

Countries

Thailand

Contacts

Public ContactBoosana Kaboosaya

Faculty of Dentistry, Chulalongkorn University

Mymascotmon@gmail.com022188581

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026