Acute exacerbation of chronic obstructive pulmonary disease diaphragmatic excursion, diaphragmatic thickness fraction, ultrasound, respiratory failure, noninvasive ventilation
Conditions
Interventions
Patients diagnosed with AECOPD were indicated for using NIV, and diaphragmatic ultrasound was performed with diaphragmatic excursion and diaphragmatic thickness fraction.
Screening
Sponsors
None listed
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients who were diagnosed with AECOPD and who were indicated for the use of NIV according to the GOLD recommendations for at least one of the following criteria were enrolled: respiratory acidosis (partial pressure of arterial carbon dioxide (PaCO2) >45 mmHg and blood pH <7.35), severe dyspnea with clinical signs of increased of breathing, and persistent hypoxemia despite supplemental oxygen therapy including high flow nasal cannula and bronchodilator therapy
Exclusion criteria
Exclusion criteria: Individuals with pulmonary edema, thoracic deformity, a history of neuromuscular diseases, indications for intubation at the beginning, who were transferred to other hospitals before intubation, who did not undergo intubation, or who did not consent to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NIV failure 48 hours requiring intubation | — |
Secondary
| Measure | Time frame |
|---|---|
| NIV duration day of discontinue NIV discontinue NIV | — |
Countries
Thailand
Contacts
Public ContactKarn Suttapanit
Faculty of Medicine Ramathibodi Hospital, Mahidol University
Outcome results
None listed