Patient with mild acne vulgaris. acne vulgaris, acne treatment
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Healthy patients with mild severity grades of acne vulgaris
Exclusion criteria
Exclusion criteria: 1. Patients with concurrent facial skin infections 2. History of allergy to the study product components. 3.History of systemic acne treatment within the 4 weeks prior to the study 4. History of oral isotretinoin within the 6 months prior to the study 5.History of topical acne treatment within the 2 weeks prior to the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Acne lesion counting baseline, 1 weeks, 4 weeks, 8 weeks Inflammatory and non-inflammatory acne counting number | — |
Secondary
| Measure | Time frame |
|---|---|
| Patients' assessment score baseline, 1 weeks, 4 weeks, 8 weeks grade 0, none; grade 1, mild; grade 2, moderate; grade 3, severe.,Investigator Global Assessment baseline, 1 weeks, 4 weeks, 8 weeks investigator global evaluation acne (IGEA),Patients' satisfaction score 8 weeks grade 0, minimum; grade 10, maximum.,Biophysical changes of skin (skin hydration, trans-epidermal water loss, pH, erythema) baseline, 1 weeks, 4 weeks, 8 weeks using Corneometer (unit from 0 (no water at all) - 120 (on water)), Tewameter (g/m2/h), pH meter(a scale of 0 to 14) and Antera3D (erythema index(unit)) | — |
Countries
Thailand
Contacts
Faculty of Medicine, Chulalongkorn University