A randomized comparative study between high- intensity laser vs low- intensity pulsed ultrasound both combined with exercises for the treatment of knee osteoarthritis in uthaithani hospital

The treatment of knee osteoarthritis can be achieved by comparing high-intensity laser vs low-intensity pulsed ultrasound and exercises in a randomized control trial

Status

Recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

TCTR

Registry ID

TCTR20240521002

Enrollment

Registered

2024-05-21

Start date

2024-05-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knee osteoarthritis exercise high intensity laser knee osteoarthritis exercise

Interventions

The control group will use the ultrasound machine BTL 4000 Smart Electro Therapy US 2.5 w/cm2, pulse ratio 1:4, frequency 1 MHz, duration 5-10 minutes, done 3 times/week for a period of 8 weeks, toget

Active Comparator Device,Experimental Device

LIPUS,HILT

Eligibility

Sex/Gender

All

Age

50 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1 Patients with grade 2-3 knee osteoarthritis diagnosed by a rehabilitation physician or orthopedic surgeon using the American College of Rheumatology criteria and radiographic criteria Kellgren-Lawrence grade 2 During the past week the knee that hurts the most is experiencing pain at a visual analog scale rating of 4 or higher 3 If both sides are hurting the side with the most pain will be chosen while the other side will be treated with standard physical therapy methods 4 When pain levels are equal on both sides the right side will be chosen while the other side is treated with standard physical therapy methods.

Exclusion criteria

Exclusion criteria: 1 Have had the following treatments within the past 3 months 1.1 Perform any type of surgery on the knee on the side that will be tested. 1.2 Injecting drugs into the knee joint 1.3 There is a severe injury to the knee on the side that will be tested. 2 have a knee infection or other chronic joint disease such as rheumatoid arthritis 3 has a serious illness that may affect the experiment 4. Have a history of neurological disease or mental health condition that may affect the experiment.

Design outcomes

Primary

Measure	Time frame
Numerical Pain Rating Scale ( 0 ,2, 4, 8 weeks score	—

Secondary

Measure	Time frame
The Western Ontario and McMaster Universities arthritis index 0 ,2, 4, 8 weeks score,Lequesne index 0 ,2, 4, 8 weeks score,40 m fast paced walk test 0 ,2, 4, 8 weeks m/sec,9 step Stair Climbing test 0 ,2, 4, 8 weeks second	—

Countries

Thailand

Contacts

Public ContactKhanin Settapaisal

Uthai Thani Hospital,Ministry of Public Health

knotkhanin@gmail.com0628299699

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026