Executive dysfunctions in individuals with Mild cognitive impairment. Feasibility study, Mixed reality, Mild cognitive impairment
Conditions
Interventions
The participants will play the Balloon Popping game using Hololens2 (Mixed reality glasses) for one hour. The objective of this game will be to pop all the virtual balloons, focusing on training diffe
Mixed reality exergame,Education
Sponsors
Faculty of Physical Therapy, Mahidol University
Eligibility
Sex/Gender
All
Age
60 Years to 90 Years
Inclusion criteria
Inclusion criteria: The inclusion criteria for healthy group will be as follows: 1) Aged 60 to 90 years old. 2) MoCA score > 24. 3) Independent walking without using gait aids. 4) No diagnosis of the dementia by clinician. The inclusion criteria for MCI groups will be as follows: 1) Aged 60 to 90 years old. 2) MoCA score between 16 to 24. 3) Independent walking without using gait aids.
Exclusion criteria
Exclusion criteria: 1) Uncontrolled high blood pressure (more than 140/90 mmHg) 2) Hemodialysis 3) Have clinical diagnosis of the disease or symptoms that could influence the performance assessments such as arthritis or severe hand pain which reports by participants and the testing by physiotherapist before testing. 4) History of neurological disorder, such as stroke or other neurodegenerative disorder 5) Taking medicine which affected to functional movement. 6) Unable to follow study protocol. 7) Uncorrected visual or hearing impairment. 8) Positive screening for contraindication of TMS which will be confirmed by TMS screening questionnaire such as uncontrolled seizures.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual attention and task switching before and immediately after intervention Trail Making Test,Inhibit control before and immediately after intervention Color-Word Stroop Test ,Single-task performance before and immediately after intervention Box and Block Test ,Dual-task performance before and immediately after intervention Box and Block with Serial Sevens Test ,Cortical outcomes before and immediately after intervention Transcranial Magnetic Stimulation,Usability immediately after Mixed reality exergaming System Usability Scale,Motivation immediately after Mixed reality exergaming Intrinsic Motivation Inventory ,Adverse side effects immediately after Mixed reality exergaming Cybersickness in Virtual Reality Questionnaire | — |
Secondary
| Measure | Time frame |
|---|---|
| N/A N/A N/A | — |
Countries
Thailand
Contacts
Public ContactRommanee Rojasavastera
Faculty of Physical Therapy, Mahidol University
Outcome results
None listed