Mucosal visibility on EGD Endoscopic mucosal visibility, Esophagogastroduodenoscopy (EGD), Simethicone dosages
Conditions
Interventions
Patients in this arm will receive 2.4 ml of normal saline, drinking at 30 minutes before performing an EGD procedure ,Patients in this arm will receive 0.6 ml(40 mg) of liquid simethicone combine with
Placebo ,Simethicone 40 mg ,Simethicone 80 mg ,Simethicone 160 mg
Sponsors
The Gastroenterological Association of Thailand
the Gastroenterological Association of Thailand.
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Chronic dyspepsia, 2. Dysphagia, 3. Esophageal varices surveillance, 4. Anemia, 5. Weight loss, 6. Vomiting, 7. Gastroesophageal reflux disease symptoms
Exclusion criteria
Exclusion criteria: 1. Upper GI bleeding, 2. Peritonitis, 3. Esophageal stricture or gastric outlet obstruction, 4. Active cardiac condition or respiratory failure, 5. Pregnancy or lactation, 6. Previous history of abdominal surgery, 7. Allergy to simethicone, 8. Not cooperate to perform an EGD
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mucosal visibility During performing an EGD mucosal visibility score | — |
Secondary
| Measure | Time frame |
|---|---|
| Add-on volume of simethicone for rescue mucosal visibility During performing an EGD procedure Volume of liquid simethicone combine with normal saline for flushing ,Duration of EGD procedure After complete exam and scope withdrawal from patient Duration of EGD procedure (minutes-seconds),Patient's satisfaction Within 30 minutes after finishing EGD procedure Visual analogue scale (0-10),Patient's safety During the study period Complications of EGD procedure and adverse effects of simethicone | — |
Countries
Thailand
Contacts
Public ContactSereephap Saeung
Suratthani Hospital
Outcome results
None listed