The anti-HBs antibody levels after vaccination with combined one dose hexavalent-based vaccine (DTaP-IPV-HB-Hib) with two doses of pentavalent-based vaccine (DTwP-HB-Hib) versus three doses of pentavalent-based vaccine (DTwP-HB-Hib) at 3-6 months after the last dose of vaccination. HBV hepatitis B virus GMT geometric mean PCV pneumococcal conjugated vaccine
Conditions
Interventions
Pentavalent group received the DTwP-HBV vaccine and an oral polio vaccine (OPV) at the age of 2 months.
Received DTwP-HBV vaccine and IPV vaccine at the age of 4 months.
Received DTwP-HBV vaccine at t
Pentavalent group,Combined hexavalent/pentavalent group
Sponsors
Research center, Faculty of Medicine Ramathibodi Hospital, Mahidol University
Eligibility
Sex/Gender
All
Age
30 Days to 120 Days
Inclusion criteria
Inclusion criteria: Infants who born at a gestational age more than 36 weeks Infants aged 30 to120 days who received a monovalent HBV vaccine at birth
Exclusion criteria
Exclusion criteria: Infants not born to HIV- or HBV-infected mothers and those with coagulopathy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anti-HBs level 3-6 months after the last dose of vaccination Blood sampling for anti-HBs level | — |
Secondary
| Measure | Time frame |
|---|---|
| Compare adverse events 7 day after each vaccination Reported by phone for gathering information | — |
Countries
Thailand
Contacts
Public ContactKantron Soonthornarrak
Faculty of Medicine Ramathibodi Hospital, Mahidol University
Outcome results
None listed