Acellular Fish Skin Graft (FSG) vs Split-Thickness Skin Graft (STSG) for oral cavity defects after surgery in Oral Cavity Cancer: Randomized Clinical Trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20240512005

Enrollment

Registered

2024-05-12

Start date

2024-01-03

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

CA Oral Cavity (stage T1,2 and 3) planned for Surgery Fish Skin Graft, Oral Cavity, Cancer

Interventions

FSG for biological dressing ,STSG for biological dressing

Experimental Device,Active Comparator Procedure/Surgery

Fish Skin Graft,STSG

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age > 18 years old, 2. CA Oral Cavity (stage T1,2 and 3) planned for Surgery at King Chulalongkorn Memorial Hospital / National Cancer Institute, 3. Defect site area < 50 % of tongue or diameter less than 5 cm and possible to do reconstruction with FSG/STSG

Exclusion criteria

Exclusion criteria: 1.Histoy Fish allergy

Design outcomes

Primary

Measure	Time frame
Inflammatory Proliferative Remodeling (IPR) Scale : IPR Scale day 5, day 14, 6 weeks scale	—

Secondary

Measure	Time frame
HN-QOL day5, day14, 6 weeks questionnaire	—

Countries

Thailand

Contacts

Public ContactThanarath Imsuwansri

National Cancer Institute

drthanarath@gmail.com0843883317

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026