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The Effect of intravenous Ascorbic acid combined with intravenous tranexamic acid in Anemia of Hemodialysis patients ; A Randomized Controlled Trial.

The Effect of intravenous Ascorbic acid combined with intravenous tranexamic acid in Anemia of Hemodialysis patients ; A Randomized Controlled Trial

Status
Unknown
Phases
Early Phase 1
Study type
Interventional
Source
TCTR
Registry ID
TCTR20240512004
Enrollment
40
Registered
2024-05-12
Start date
2024-04-27
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemodialysis patients which has Anemia of inflammation Intravenous Ascorbic acid, Intravenous tranexamic acid, Anemia in hemodialysis patients

Interventions

20 patients received injections of intravenous ascorbic acid and tranexamic acid during hemodialysis.,20 patients received intravenous ascorbic acid and saline solution during hemodialysis.
Experimental Drug,Experimental Drug

Sponsors

Buriram Hostpital, Thailand
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Kidney failure patients undergoing hemodialysis treatment with hemodialysis who have anemia from inflammatory processes in the body with a hemoglobin level less than or equal to 11 g/dl, a serum ferritin level greater than 800 ng/ml, and a serum transferrin saturation greater than or equal to 40%.

Exclusion criteria

Exclusion criteria: 1) Patients with end stage kidney disease receiving kidney replacement therapy with hemodialysis who have a history of epilepsy. or have had a history of brain surgery 2) Patients with urinary tract stone problems 3) Patients who are allergic to vitamin C injectable form and allergic to tranexamic acid. 4) Patients who have received iron injections within the past 2 months. 5) Patients who refuse to participate in the study

Design outcomes

Primary

MeasureTime frame
Serum iron, Feritin, Total iron binding capacity, Hematocirt 6 months micromol/L, %Tranferin saturation

Secondary

MeasureTime frame
intact Parathyroid hormone, C-reactive protein, Erythrocyte Sedimentation rate, uric acid 6 months pg/ml, mg/L, mm/h, mg/dl(micromol/L)

Countries

Thailand

Contacts

Public ContactTheerapun Boonsayomphu

Buriram Hospital

theerapun3939@gmail.com0853113939

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026