Comparison of meibomian gland dysfunction in entropion patient after treatment with Quickert suture and medical treatment

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

TCTR

Registry ID

TCTR20240507002

Enrollment

Registered

2024-05-07

Start date

2024-10-31

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spastic or involutional entropion patients with meibomian gland dysfunction requiring eyelid surgery. spastic entropion, involutional entropion, meibomian gland dysfunction, Quickert suture, dry eye, lipid layer thickness, tear stability

Interventions

The patient will receive a quickert suture in the study eyelid, as well as medical treatment and lid hygiene scrubs as described in the second arm of the trial. ,The patient will not receive a quicke

Experimental Procedure/Surgery,No Intervention Drug

Quickert suture,Medication only

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Thai citizens who are 18 years of age and above 2. Spastic or involutional entropion with meibomian gland dysfuction 3. Require entropion eyelid surgical repair

Exclusion criteria

Exclusion criteria: 1. History of eyelid surgery 2. Appointment of eyelid surgery is within the next 6 months 3. Chronic inflammatory eye diseases that are poor controlled, such as Thyroid eye disease or Steven Johnson syndrome 4. Allergic to fluorescein 5. The patient is unable to follow up as per protocol 6. The patient is unable to communicate the ocular symptoms 7. The patient denys further treatment

Design outcomes

Primary

Measure	Time frame
Meibomian gland dropout Baseline, 1 week, 1 month, 3 months, 6 months Grading system by Gestalt method,Lower eyelid lipid layer thickness Baseline, 1 week, 1 month, 3 months, 6 months Interferometry color unit (ICU)	—

Secondary

Measure	Time frame
Lid margin abnormalities: Telangiectasia, irregularity, thickness, plugging Baseline, 1 week, 1 month, 3 months, 6 months score,Fluorescein staining Baseline, 1 week, 1 month, 3 months, 6 months score,Fluorescein breakup time Baseline, 1 week, 1 month, 3 months, 6 months seconds,Schirmer test Baseline, 1 week, 1 month, 3 months, 6 months millimeters,Tear meniscus height Baseline, 1 week, 1 month, 3 months, 6 months millimeters,Meibum grade Baseline, 1 week, 1 month, 3 months, 6 months grade,Expressed meibum color: upper eyelid, lower eyelid Baseline, 1 week, 1 month, 3 months, 6 months grade,Expressed meibum consistency: upper eyelid, lower eyelid Baseline, 1 week, 1 month, 3 months, 6 months grade	—

Measure

Time frame

Lid margin abnormalities: Telangiectasia, irregularity, thickness, plugging Baseline, 1 week, 1 month, 3 months, 6 months score,Fluorescein staining Baseline, 1 week, 1 month, 3 months, 6 months score,Fluorescein breakup time Baseline, 1 week, 1 month, 3 months, 6 months seconds,Schirmer test Baseline, 1 week, 1 month, 3 months, 6 months millimeters,Tear meniscus height Baseline, 1 week, 1 month, 3 months, 6 months millimeters,Meibum grade Baseline, 1 week, 1 month, 3 months, 6 months grade,Expressed meibum color: upper eyelid, lower eyelid Baseline, 1 week, 1 month, 3 months, 6 months grade,Expressed meibum consistency: upper eyelid, lower eyelid Baseline, 1 week, 1 month, 3 months, 6 months grade

—

Countries

Thailand

Contacts

Public ContactFahsiri Tavonvunchai

Mettapracharak Hospital

fahsiri.t@gmail.com0830024928

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026