Toll-like receptor-8 mRNA expression as a predictor of enterocolitis in hirschsprung disease: a cross-sectional study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

TCTR

Registry ID

TCTR20240504002

Enrollment

Registered

2024-05-04

Start date

2023-01-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with the incidence of enterocolitis in Hirschsprung Disease who underwent surgical procedures under anesthesia during the study period were included in this study. Hirschsprung Disease Paediatric Surgery mRNA TLR-8

Interventions

Hirschsprung&#039

s disease without enterocolitis, confirmed by immunohistochemistry examination ,Hirschsprung&#039

s disease with enterocolitis, confirmed by immunohistochemistry examination

Basic Science,Basic Science

Group 1,Group 2

Eligibility

Sex/Gender

All

Age

1 Weeks to 18 Years

Inclusion criteria

Inclusion criteria: Patient with enterocolitis in Hirschsprung Disease

Exclusion criteria

Exclusion criteria: Patient enterocolitis in Hirschsprung Disease with other disease

Design outcomes

Primary

Measure	Time frame
mRNA Expression Toll-Like Receptor-8 When patients underwent surgery Fold change mRNA expression	—

Secondary

Measure	Time frame
Characteristic data When patien admitted to our hospital age, sex, and grading enterocolitis	—

Countries

Indonesia

Contacts

Public ContactNita Mariana

Hasanuddin University

nita.el.suhel@gmail.com062411585984

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026