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Inflammatory responses of peri-implant crevicular fluid on different dental implant abutment materials after 6-months functional loading: A randomized clinical controlled trial

Inflammatory responses of peri-implant crevicular fluid on different dental implant abutment materials after 6-months functional loading: A randomized clinical controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20240501003
Enrollment
16
Registered
2024-05-01
Start date
2023-06-10
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Age 18 - 60 years old. Healthy or with well-controlled systemic diseases. Patients who have been treated with single tooth implant in esthetic zone either with or without bone graft on anterior teeth including upper or lower canines, lateral incisors and central incisors at crestal bone level. Screw retained or screw-cement retained implants. Sufficient keratinized gingiva of width of at least 4 mm. Undergone oral prophylaxis treatment and instructions after implant placement. implant abut

Interventions

Eight patients were installed with titanium abutment on the day of implant crown placement.,Eight patients were installed with titanium base abutment on the day of implant crown placement.
Treatment,Treatment
Titanium abutment,Titanium base abutment

Sponsors

Faculty of Dentistry, Chulalongkorn University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. healthy or with well-controlled systemic diseases, 2. patients who have been treated with single tooth implant in esthetic zone (Neodent-Straumann or Straumann, Switzerland) either with or without bone graft on anterior teeth including upper or lower canines, lateral incisors and central incisors at crestal bone level, 3. screw retained or screw-cement retained implants, 4. sufficient keratinized gingiva of width of at least 4 mm, and 5. undergone oral prophylaxis treatment and instructions after implant placement.

Exclusion criteria

Exclusion criteria: 1. medical or general contraindication to the surgical procedure (American Society of Anesthesiologists (ASA) status III), 2. smokers (at least 10 cigarettes per day), 3. poor plaque control or having untreated active periodontal disease, 4. having acute infection including severe swelling of the gingiva, suppuration, and abscess, and 5. being pregnant.

Design outcomes

Primary

MeasureTime frame
Concentrations of inflammatory markers before and after 6 months of functional loading Enzyme-linked immunosorbent assays (ELISAs),Clinical responses before and after 6 months functional loading Assessment of probing pocket depth, plaque control, bleeding on probing, and suppuration. ,Radiographic responses before and after 6 months functional loading Periapical radiograh

Secondary

MeasureTime frame
N/A N/A N/A

Countries

Thailand

Contacts

Public ContactWareeratn Chengprapakorn

Faculty of Dentistry, Chulalongkorn University

wchengprapakorn@gmail.com022188664

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026