Asthma Asthma Aerobic exercise Oxidative stress Inflammation Physical fitness Asthma control Quality of life Respiratory muscle strength Pulmonary function
Conditions
Interventions
Participants in the control group will be instructed to carry out their normal physical activity for 12 weeks.,Participants in the training group will be instructed to carry out step aerobic exercise
No Intervention Other,Experimental Other
Sponsors
Faculty of Medicine, Khon Kaen University, Thailand
Eligibility
Sex/Gender
All
Age
20 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Women or men are diagnosed with asthma according to GINA guidelines 2. Age 20-65 years 3. Non regular exercise (less than 3 times/week and less than 30 min/day) 4. Participants receive stable dose of asthmatic drug at least 1 month before participation of the study. 5. Sedentary lifestyle
Exclusion criteria
Exclusion criteria: 1. There are other respiratory diseases such as chronic obstructive pulmonary disease and respiratory tract infection. 2. There are exacerbation within 1 month before participation of the study. 3. Congestive heart failure, angina pectoris 4. There are abnormal of muscle and bone affecting movement of knee and ankle. 5. Presence of neuromuscular conditions interfering with the ability to perform step aerobic exercise such as herniated disc and muscle weakness
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Asthma control Pre, intermediate, and post exercise training Asthma control questionnaire and Asthma control test,Quality of life Pre, intermediate, and post exercise training Quality of life questionnaire,Exercise capacity Pre, intermediate, and post exercise training Assessment of distance walked over 6 minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| Oxidative stress Pre, intermediate, and post exercise training Malondialdehyde and catalase,Airway inflammation Pre, intermediate, and post exercise training Fractional exhaled nitric oxide,Systemic inflammation Pre, intermediate, and post exercise training High sensitivity C-reactive protein, IL5, CBC,Pulmonary function Pre, intermediate, and post exercise training Lung volumes and flow rates,Physical performance Pre, intermediate, and post exercise training Timed up and go test, single leg stance test, thirty-second chair stand test, walking speed,Respiratory muscle strength Pre, intermediate, and post exercise training Maximal inspiratory pressure and maximal expiratory pressure | — |
Countries
Thailand
Contacts
Public ContactOrathai Tunkamnerdthai
Faculty of Medicine, Khon Kaen Universtiy, Thailand
Outcome results
None listed