EFFECTIVENESS OF SILVER DIAMINE FLUORIDE WITH LIGHT CURE IN ARRESTING DENTIN CARIES IN PRIMARY TEETH: RANDOMIZED CLINICAL TRIAL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20240422003

Enrollment

256

Registered

2024-04-22

Start date

2024-04-30

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy children have at least one pair of active cavitated enamel and dentin caries (Nyvad score 3) at least one pair. The pair of caries were had to be of the similar size, same type, same position (anterior/posterior) and same caries surface involvement buccal/palatal/occlusal/incisal/mesial/distal) at the contralateral side. Silver Diamine Fluoride, Light, Dental caries, good health &amp

Interventions

Apply Silver diamine fluoride for 60 seconds on carious lesion,Apply Silver diamine fluoride for 10 seconds following light cure for 20 seconds on carious lesion

Active Comparator Device,Active Comparator Device

Silver Diamine Fluoride ,Silver diamine fluoride with light cure

Eligibility

Sex/Gender

All

Age

2 Years to 5 Years

Inclusion criteria

Inclusion criteria: 1. Healthy children 2. They have at least one pair of active cavitated enamel and dentin caries (Nyvad score 3) at least one pair. The pair of caries were had to be of the similar size, same type, same position (anterior/posterior) and same caries surface involvement buccal/palatal/occlusal/incisal/mesial/distal) at the contralateral side. If the adjacent anterior teeth were treated with either treatment, the caries surfaces would not be adjacent. 3. No history of allergies to silver, ammonia, or fluoride. 4. Caregiver and children accept to take part in the study consent. 5. Children can come to follow up after 6 and 12 months of treatment.

Exclusion criteria

Exclusion criteria: 1. Children are uncooperative in treatment. 2. Teeth have symptoms of pulpitis or infection such as pain or gingival abscess. 3. Children cannot come for follow-up or their caregivers did not want to continue in the study.

Design outcomes

Primary

Measure	Time frame
Arrested caries 6 and 12 months Clinical examination by using Nyvad Criteria	—

Secondary

Measure	Time frame
Factors related arrested caries 12 month Questionnaire	—

Countries

Thailand

Contacts

Public ContactNuttha Wannapaka

Pediatric dentistry, Faculty of Dentistry, Chulalongkorn University

wannapaka.nuthha@gmail.com0855649546

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026