periodontitis periodontal disease, oxidative stress, root planing, tumor necrosis factor alpha
Conditions
Interventions
Oral hygiene instructions (OHI) and motivation sessions were given to each patient. OHIs were reinforced during each treatment session and follow-up visits. The treatment protocol was as follows
supragingival and subgingival mechanical instrumentation of the root surface was performed by a single periodontist (SB), using both hand (Gracey Periodontal Currettes (Hu-Friedy)) and ultrasonic inst
under local anaesthesia.Q was performed one quadrant per session, with an interval of 1 week between instrumentation sessions for a total of 3 weeks. ,Oral hygiene instructions (OHI) and motivation se
under local anaesthesia. FM was performed within a single session.
Active Comparator Procedure/Surgery,Active Comparator Procedure/Surgery
Quadrant-wise subgingival instrumentation ,Full mouth subgingival instrumentation
Sponsors
Sebnem bilir ikiz
Eligibility
Sex/Gender
All
Age
25 Years to No maximum
Inclusion criteria
Inclusion criteria: aged 25 and above, systemically healthy and lifelong non smokers ,at least had 20 teeth, diagnosis of moderate-advanced periodontitis
Exclusion criteria
Exclusion criteria: pregnant or lactating females, had a diagnosis of any systemic disease as diabates, had removable prosthesis and had undergone periodontal treatment or used antibiotics in the last 6 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total antioxidant status, total oxidant status 3 months ELISA kit as mmol Trolox Equivalents/L ELISA kit as micromoles of hydrogen peroxide equivalents per liter | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical measurements, Tumor Necrosis Factor alpha 3 months ELISA kit (Eastbiopharm - Human TNF-alpha Platinum ELISA, Cat No: CK-E10110) The outcomes were quantified and reported in nanograms per liter (ng/L). | — |
Countries
Turkey
Contacts
Public ContactSEBNEM BILIR IKIZ
ISTANBUL UNIVERSITY
Outcome results
None listed