Participants who diagnose with benign gynecologic conditions and scheduled for total abdominal hysterectomy with or without adnexal surgery. Postoperative nausea and vomiting, PONV, dexamethasone, hysterectomy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Participants were diagnosed with benign gynecologic conditions and scheduled for total abdominal hysterectomy with or without adnexal surgery.
Exclusion criteria
Exclusion criteria: 1.Had a known hypersensitivity to dexamethasone 2. Had conditions that might influence gastrointestinal motility (including previous bowel surgery, previous abdominal irradiation, chronic constipation, pancreatitis, peritonitis, hypothyroidism, and chronic use of drugs that impact intestinal peristalsis 3. Had underlying diabetes mellitus who got poor glycemic control 4. Were immunocompromised (tuberculosis, HIV Infection) 5. Experienced an intraoperative blood loss of more than 1,000 ml or blood loss that required blood transfusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of PONV within 24 hours at 24 hours after receiving the intervention Percent | — |
Secondary
| Measure | Time frame |
|---|---|
| Additional Drug Requirements within 24 hours after receiving intervention Percent,Side effects of dexamethasone within 24 hours after receiving intervention Percent,Postoperative pain score at 24 hours after receiving intervention Mean,This length of hospital stay After participants were discharge from hospital Mean | — |
Countries
Thailand
Contacts
Khon Kaen Hospital