An Experimental Study on the effect of biotin on Measurement of FT3, FT4 and TSH in healthy adults

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

TCTR

Registry ID

TCTR20240411004

Enrollment

Registered

2024-04-11

Start date

2023-08-22

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy Adults Biotin, Thyroid interference, Discordance of Thyroid function test

Interventions

FT4, FT3, and TSH Test from Beckman Coulter DXI800 ,FT4, FT3, and TSH Test from Cobas Elecsys e801

Active Comparator Dietary Supplement,Sham Comparator Dietary Supplement

Beckman Coulter DXI800,Cobas Elecsys e801

Eligibility

Sex/Gender

All

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Healthy Adult without underlying disease

Exclusion criteria

Exclusion criteria: 1. History of Allergy to Biotin 2. Pregnancy 3. Breast Feeding 4. Abnormal Thyroid function test or History of Thyroid disease 5. Taking Weight loss supplement 6. Taking Medication that contain Thyroid hormone, Biotin, and Medication that interfere thyroid function test such as amiodarone, carbamazepine within 1 month 7. Taking Supplement, Vitamin within 1 month 8. Smoking 9. History of Severe illness or admitted in hospital within 2 months

Design outcomes

Primary

Measure	Time frame
Change in FT3, FT4, TSH Before and After taking Biotin At the beginning of study, Day 7, Day 14 ng/dL	—

Secondary

Measure	Time frame
Comparison of percentage of FT3, FT4, TSH blood test results that were disturbed by Biotin between Beckman Coulter DXI800 and Cobas Elecsys e801. At the beginning of study, Day 7, Day 14 ng/dL	—

Countries

Thailand

Contacts

Public ContactApanaree Bhekasuta

SOMDECH PHRA NANGCHAO SIRIKIT HOSPITAL

ploypds@gmail.com0994178226

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026