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A study of the incidence of molecular mutations in newly diagnosed acute lymphoblastic leukemia (ALL) patients by Next-generation sequencing technique

A study of the incidence of molecular mutations in newly diagnosed acute lymphoblastic leukemia (ALL) patients by Next-generation sequencing technique

Status
Unknown
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20240409003
Enrollment
140
Registered
2024-04-09
Start date
2022-10-03
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thai newly diagnosed ALL patients aged greater than 18 years. Acute lymphoblastic leukemia, Next-generation sequencing ,Molecular mutations

Interventions

Retrospective and prospective cohort who newly diagnosed ALL patients aged greater than 18 years. who signed consent in Protocol title The newly diagnosed acute lymphoid leukemia registry and ribonu
Diagnostic
Thai newly diagnosed ALL patients aged greater than 18 years

Sponsors

Siriraj Hospital Mahidol University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.A retrospective cohort: Thai newly diagnosed ALL patients 2.A prospective cohort: Thai newly diagnosed ALL patients aged greater than 18 years who had genetic workup results by NGS study and signed informed consent OR

Exclusion criteria

Exclusion criteria: Poor quality specimen from a protocol number 388/2561(EC2)

Design outcomes

Primary

MeasureTime frame
incidence of molecular mutations in Thai adult newly diagnosed ALL patients by NGS technique 1 years Next-generation sequencing (targeted gene sequencing: Illumina machine)

Secondary

MeasureTime frame
To evaluate the clinical outcome in Thai adult ALL patients considering molecular mutations 1 years Case record form comparing with genetic results by Illumina machine

Countries

Thailand

Contacts

Public ContactWeerapat Owattanapanich

Faculty of Medicine Siriraj Hospital, Mahidol University.

weerapato36733@gmail.com0891081983

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026