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A pragmatic non-randomized trial comparing of 10% Dextrose and 50% Dextrose for the treatment of hypoglycemic patients

A pragmatic non-randomized trial comparing of 10% Dextrose and 50% Dextrose for the treatment of hypoglycemic patients.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20240404005
Enrollment
165
Registered
2024-04-04
Start date
2023-12-02
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypoglycemic adults who were visiting the emergency department Hypoglycemia Emergency departments Dextrose

Interventions

A 1000 ml bag of 10% dextrose in 0.45% sodium chloride solution was drawn with a 50 ml syringe from the bag via an IV set connected with a three-way stopcock and extension tube for the treatment of hy
10% dextrose 15 grams,10% dextrose 20 grams,50% dextrose in water

Sponsors

Somdejphrajoataksinmaharaj Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 120 Years

Inclusion criteria

Inclusion criteria: 1.Adults aged 18 years and older who experienced hypoglycemia, defined as a finger stick capillary blood glucose level less than 70 mg/dL. 2. Individuals with abnormal levels of consciousness or those recommended for intravenous glucose treatment by a treating physician despite normal consciousness. 3.Patients who were treated for hypoglycemia according to the study protocol and then brought to the emergency department by advanced life support teams were included, as well as patients who visited the emergency department directly.

Exclusion criteria

Exclusion criteria: 1.A patient who was in cardiac arrest 2. A treating physician or lead member of the advanced life support team suspected impending or ongoing respiratory failure due to volume overload

Design outcomes

Primary

MeasureTime frame
The proportion of patients who had capillary blood glucose levels within 80-180 mg/dL after intravenous glucose bolus. At 15 minutes and 60 minutes after iv bolus glucose Measure the number of patients who had finger stick capillary blood glucose levels within 80-180 mg/dL.

Secondary

MeasureTime frame
The mean capillary blood glucose level after treatment with intravenous glucose bolus 15 minutes and 60 minutes after initial intravenous glucose bolus Capillary blood glucose at 15 minutes and 60 minutes ,Incident of patients who had hypervolemia and required treatment within 24 hours after the initial intravenous glucose bolus 24 hours after the initial treatment of the intravenous glucose bolus or at discharge if it occurred before 24 hours The number of patients who were treated with intravenous diuretics or emergency hemodialysis, which are not part of the regular cycle for routine hemodialysis of the patient,The mean difference of capillary blood glucose from baseline 15 minutes and 60 minutes after initial intravenous glucose bolus Mean difference of capillary blood glucose after treatment from baseline capillary blood glucose

Countries

Thailand

Contacts

Public ContactKanjanee Wachirarangsiman

Somdejphrajoataksinmaharaj Hospital

kanjanee30@gmail.com0817060962

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026