Body composition change in people living with HIV after transition antiretroviral therapy from TDF/FTC/EFV to TDF/3TC/DTG

Body composition change in people living with HIV after transition antiretroviral therapy from TDF/FTC/EFV to TDF/3TC/DTG. A randomized control trial

Status

Unknown

Phases

Phase 1

Study type

Interventional

Source

TCTR

Registry ID

TCTR20240404003

Enrollment

170

Registered

2024-04-04

Start date

2023-10-27

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Body composition in people living with HIV after changing ARV from TDF/FTC/EFV to TDF/3TC/DTG Body composition, metabolic, HIV, TEEVIR, Acriptega

Interventions

Change ARV regimen from TDF/FTC/EFV to TDF/3TC/DTG ,Continue ARV regimen TDF/FTC/EFV

Active Comparator Drug,No Intervention Drug

Change ARV to TDF/3TC/DTG ,Continue TDF/FTC/EFV

Eligibility

Sex/Gender

All

Age

20 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patient living with HIV who can come follow up at Ramathibodi Hospital 2. Prescribed TDF/FTC/EFV at least 6 mo. prior include in this study 3. Age > 20 yr 4. HIV viral load <200 copies/mL 5. CD4 level > 200 cells/mL 6. Accept to join the project by signing the consent

Exclusion criteria

Exclusion criteria: 1. Follow up less than 2 times after join the project 2. Got pregnant during join the project 3. Got infected by opportunistic infection during join the project 4. Not viable for measured body composition using bioelectrical impedance analysis machine

Design outcomes

Primary

Measure	Time frame
Body composition change 8 month Bioelectrical impedance analysis	—

Secondary

Measure	Time frame
Metabolic profile 8 month Fasting blood sugar, Lipid profile	—

Countries

Thailand

Contacts

Public ContactWarut Kajornrith

Faculty of medicine Ramathibodi, Mahidol university

warutmui@gmail.com0896978544

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026