Elderly (60-80 years old) undergoing Transurethral Resection of the Prostate under spinal anesthesia dexmedetomidine, elderly, Transurethral Resection of the Prostate, TURP, spinal anesthesia, prolong, intravenous
Conditions
Interventions
intravenous Dexmedetomidine 0.4 mcg/kg total 10 ml,intravenous NSS 10 ml
Experimental Drug,Placebo Comparator No treatment
Dexmedetomidine group,NSS group
Sponsors
Faculty of Medicine Ramathibodi Hospital, Mahidol University
Eligibility
Sex/Gender
Male
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Age 60-80 years 2.ASA physical status 1-3 3.undergoing Transurethral Resection of the Prostate under spinal anesthesia 4.inform consent before 5.pass cut-off point of MMSE-Thai 2002 for cognitive impairment
Exclusion criteria
Exclusion criteria: 1.patient refuse to participate 2.contraindication to spinal anesthesia 3.allergy to drug in trial 4.liver cirrhosis 5.end stage renal disease 6.Bradycardia ((heart rate <=50 bpm))
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Two-dermatome regression until Two-dermatome regression Two-dermatome regression test every 10 min | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual analog scale 0, 6, 12, 24 hours Visual analog scale | — |
Countries
Thailand
Contacts
Public ContactChatchayapa Rathanasutthajohn
Faculty of medicine Ramathibodi Hospital, Mahidol University
Outcome results
None listed