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Comparison of postoperative urinary retention and pain control between intrathecal nalbuphine and intrathecal morphine in anorectal surgery

Comparison of postoperative urinary retention and pain control between intrathecal nalbuphine and intrathecal morphine in anorectal surgery

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20240328010
Enrollment
300
Registered
2024-03-28
Start date
2022-08-29
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Urinary retention Pain score Nausea &amp

Interventions

0.5% hyperbaric bupivacaine + intrathecal Nalbuphine 0.2 mg,0.5% hyperbaric bupivacaine 5-10 mg + morphine 0.15 mg,0.5% hyperbaric bupivacaine 5-10 mg
0.5% hyperbaric bupivacaine 5-10 mg + intrathecal Nalbuphine 0.2 mg,0.5% hyperbaric bupivacaine 5-10 mg + intrathecal morphine 0.15 mg,0.5% hyperbaric bupivacaine 5-10 mg

Sponsors

None listed

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Age 18-65 years old 2. ASA physical status I-III 3. Undergoing elective anorectal surgery with spinal anesthesia at Chulalongkorn Hospital

Exclusion criteria

Exclusion criteria: 1. Allergies to drugs used in the study 2. Inability to provide pain scores 3. History of prior urinary catheterization 4. Chronic pain persisting beyond 3 months and prior exposure to morphine 5. Presence of skin diseases and itching 6. The requirement for critical care post-surgery 7. Contraindications to the specific spinal anesthesia employed in the study

Design outcomes

Primary

MeasureTime frame
Incidence of urinary retention 24 hour percentage

Secondary

MeasureTime frame
Pain score (movement & rest) 24 hour numeric rating scale,Nausea & vomiting 24 hour Nausea & Vomiting score,Pruritus 24 hour Verbal rating scale,Sedation 24 hour Ramsay sedation scale

Countries

Thailand

Contacts

Public ContactWasin Boonnitchasin

King Chulalongkorn Memorial Hospital

wasinwu@gmail.com0811035101

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026