FindTrial
Sign In

The comparison of circuit lifespan between integration and separation approach in extracorporeal membrane oxygenation (ECMO) patient requiring continuous renal replacement therapy (CRRT) support, (E-CRRT Trial)

The comparison of circuit lifespan between integration and separation approach in extracorporeal membrane oxygenation (ECMO) patient requiring continuous renal replacement therapy (CRRT) support, (E-CRRT Trial)

Status
Unknown
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20240324001
Enrollment
80
Registered
2024-03-24
Start date
2022-05-01
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The critically ill ECMO patient who has acute kidney injury requires continuous renal replacement therapy (CRRT). CRRT, ECMO, circuit, combination, integration

Interventions

The CRRT circuit combined into ECMO circuit at P2 segment,The parallel separation of the CRRT circuit and ECMO circuit
Experimental Procedure/Surgery,Active Comparator Procedure/Surgery
Integration group,Separation group

Sponsors

Excellence Center for Critical Care Nephrology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients aged 18 years or older, 2. Admitted to the intensive care unit, 3. Requiring ECMO (venovenous (VV-ECMO) or venoarterial ECMO (VA-ECMO), and 4. Presenting with AKI, which needs CRRT.

Exclusion criteria

Exclusion criteria: 1. Pregnancy 2. Heparin contraindication 3. AKI due to bilateral renal arterial thrombosis, renal vasculitis, glomerulonephritis, systemic vasculitis, or post-obstructive renal failure

Design outcomes

Primary

MeasureTime frame
Circuit lifespan of Continuous Renal Replacement Therapy (CRRT) at 72 hrs post initiated Continuous Renal Replacement Therapy hour—

Secondary

MeasureTime frame
28-day mortality 28 days day,serious adverse events Day 0, Day 1, Day 2, and Day 3 event,Circuit Pressure of Continuous Renal Replacement Therapy Day 0, Day 1, Day 2, and Day 3 mmHg,Machine Alarm of Continuous Renal Replacement Therapy Day 0, Day 1, Day 2, and Day 3 time—

Countries

Thailand

Contacts

Public ContactPrasittiporn Tangjitaree

Faculty of Medicine, Chulalongkorn University

pingmazz@gmail.com022564000

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026