Optimal End-Tidal Sevoflurane concentration in patients with shock undergoing general anesthesia

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

TCTR

Registry ID

TCTR20240321004

Enrollment

Registered

2024-03-21

Start date

2022-08-22

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with shock Patient with shock Sevoflurane MAC of sevoflurane End tidal of sevoflurane

Interventions

Definition of shock 1. Capillary refill time less than2 second 2. Urine Output less than 0.5 ml/kg/hr 3. Lactate Levels more than2 mmol/L 4. Use of Vasopressors or Inotropes to Maintain MAP more than

Treatment

Observation group

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 65 years old 2. Patients with shock undergoing general anesthesia

Exclusion criteria

Exclusion criteria: 1. Decline to participate in the study 2. Pregnancy 3. History of seizures 4. History of Malignant hyperthermia 5. History of regular alcohol consumption 6. Patients with neurological conditions 7. End-stage kidney or liver disease 8. Who are unable to apply bispectral index monitor

Design outcomes

Primary

Measure	Time frame
sevoflurane concentration Intraoperation End tidal and Minimum alveolar concentrations	—

Secondary

Measure	Time frame
Minimum alveolar concentration of seoflurane in patients with shock Intraoperation MAC	—

Countries

Thailand

Contacts

Public ContactThanarattana Thammavech

Faculty of Medicine, KhonKaen university

Thanarattana.t@kkumail.com0897323117

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026