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Prospective trial of esophagogastroscopy versus thoracic computed tomography in prediction of upper gastrointestinal tract stricture after caustic ingestion

Prospective trial of esophagogastroscopy versus thoracic computed tomography in prediction of upper gastrointestinal tract stricture after caustic ingestion

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20240320009
Enrollment
30
Registered
2024-03-20
Start date
2022-09-15
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Caustic ingestion Burns, Caustics, Caustic ingestion, Chemical, Computed Tomography, Corrosive injury, Endoscopy, Esophageal injury, Esophageal stricture, Esophagogastroscopy, Gastric outlet obstruction

Interventions

All patients had endoscopy and CT within 48-hour period. EGD was performed by an experienced trauma surgeon. Mucosal damage was classified using Zargar classification. CT chest was also conducted with
Screening
Caustic ingestion patients

Sponsors

Faculty of Medicine, Thammasat University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients who have experienced caustic ingestion within 24 hour

Exclusion criteria

Exclusion criteria: 1. Previous surgery of esophagus or stomach, 2. Patients with esophageal or gastric cancer, 3. Patients with hemodynamic instability and not respond to adequate resuscitation, 4. Physical examination suggests perforated viscus or airway (eg., subcutaneous emphysema), 5. Plain films reveal perforated viscus or airway

Design outcomes

Primary

MeasureTime frame
The ability of endoscopy and CT scanning in predicting caustic strictures 3 weeks following caustic ingestion AUROC (Area Under the Receiver Operating Characteristic) curve

Secondary

MeasureTime frame
Sensitivity, specificity, positive predictive value, negative predictive value of endoscopy and CT scanning in predicting caustic strictures. 3 weeks following caustic ingestion Sensitivity, specificity, positive predictive value, negative predictive value

Countries

Thailand

Contacts

Public ContactThanyaporn Suksumek

Faculty of Medicine, Thammasat University

thanyaf@tu.ac.th0831974238

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026