Ovarian cancer with adjuvant chemotherapy Ovarian cancer , Adjuvant chemotherapy, Curcumin, C-reactive protein
Conditions
Interventions
Adjuvant chemotherapy with Abhaibhubejhr'
s curcumin capsules 400 mg/capsule ,per oral 2 tablets , 4 times after breakfast, lunch, dinner and before bed every day for a period of 8 weeks.,Adjuvant chemotherapy alone
Experimental Drug,Experimental Drug
Curcumin,Standard treatment
Sponsors
Faculty of Medicine, Khon Kaen University
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with ovarian cancer based on pathological biopsy results that have been reported by a pathologist. 2. New patients who plan to start receiving first line adjuvant chemotherapy after surgery. 3. Patients receiving treatment at Srinagarind Hospital Khon Kaen University. 4. Patients who are older than or equal to 18 years old.
Exclusion criteria
Exclusion criteria: 1. Patients who do not consent to participate in research. 2. Patients who received neo-adjuvant chemotherapy or concurrent chemo-radiation. 3. Patients with a history of herbal allergies. 4. Patients with abnormal liver function values (bilirubin more than or equal 2.0 mg/dL). 5. Patients with abnormal kidney function values (creatinine more than or equal 2.0 mg/dL). 6. Patients with an unstable medical condition including unstable heart failure, uncontrolled arrhythmias, uncontrolled coagulopathy, brain metastasis and uncontrolled epilepsy. 7. Patients with bile duct disease such as bile duct stones, bile duct cancer or obstructive bile duct from various causes. 8. Pregnant women 9. Patients taking anticoagulants and antiplatelet drugs. 10. Patients receiving chemotherapy drugs such as doxorubicin, chlormethine, cyclophosphamide and camptothecin (refer to the curcumin capsules package insert Abhaibhubejhr Seal that you should be careful when using the drug together with certain cancer drugs because they may have an adverse effect on the drugs)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| C-reactive protein Monitor C-reactive protein before starting chemotherapy for the first , second and third chemotherapy session. Blood testing for C-reactive protein level | — |
Secondary
| Measure | Time frame |
|---|---|
| side effects of curcumin before starting chemotherapy for the second, third and fourth chemotherapy session. Common Terminology Criteria for Adverse Events v3.0 (CTCAE) | — |
Countries
Thailand
Contacts
Public ContactThananya Wannasarn
Faculty of Medicine, Khon Kaen University
Outcome results
None listed