Pregnant women age between 20-39 year. Volunteers are lean pregnant women with preeclampsia and without preeclampsia and obese pregnant women which will be sub-divided into two groups including uncomplicated maternal obesity and preeclamptic maternal obesity. Maternal obesity, oxidative stress, antioxidant, inflammation, placenta
Conditions
Interventions
Pregnant women whose BMI before pregnancy was within the normal range, No preeclampsia.
,Pregnant women who have a pre-pregnancy BMI higher than normal and do not have preeclampsia.,Pregnant women who
Uncomplicated lean group (Control group),Uncomplicated obesity group,Preeclamptic lean group,Preeclamptic obesity group
Sponsors
Khon Kaen University
Eligibility
Sex/Gender
Female
Age
20 Years to 39 Years
Inclusion criteria
Inclusion criteria: 1. Pregnant women were divided into four groups including preeclamptic obesity group, preeclamptic lean, uncomplicated obesity, and uncomplicated lean. 2. Singleton pregnancy 3. Normal vaginal delivery or cesarean delivery 4. No history of smoking, alcoholism, or exposure to teratogenic substances 5. No history of chronic diseases including chronic hypertension, diabetes mellitus, kidney, liver, immune and respiratory diseases, infections, and fetal anomalies
Exclusion criteria
Exclusion criteria: 1) Newborn abnormalities 2) Low birth weight (defined as birth weight below 1000 g) 3) Obstetric complications during delivery and postpartum including uterine rupture retained placenta and postpartum hemorrhage
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Biomarker Placenta tissue, Maternal blood and umbilical cord blood, collected immediately after delivery, and biomarker analysis Biochemical assessment | — |
Secondary
| Measure | Time frame |
|---|---|
| Anthropometric data Anthropometric data were collected from volunteers during the postpartum recovery period while they were admitted to the hospital ward. questionaire | — |
Countries
Thailand
Contacts
Public ContactSophida Phuthong
FACULTY OF MEDICINE, KHON KAEN UNIVERSITY
Outcome results
None listed