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Comparison the effect of isotonic and hypotonic saline solution for children with dehydration in Lampang hospital

Comparison the effect of isotonic and hypotonic saline solution for children with dehydration in Lampang hospital

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
TCTR
Registry ID
TCTR20240316002
Enrollment
144
Registered
2024-03-16
Start date
2023-11-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Isotonic intravenous replacement can use safely and no crucial complication in acute ill pediatric patients with mild dehydration mild dehydration Hyponatremia Hypernatremia

Interventions

Isotonic solution is 5DNSS,Hypotonic solution is 5DN2
Active Comparator Drug,Active Comparator Drug
Isotonic solution,Hypotonic solution

Sponsors

None listed

Eligibility

Sex/Gender
All
Age
6 Months to 15 Years

Inclusion criteria

Inclusion criteria: patients aged 6 months to 15 years with acute illness and mild dehydration. They received intravenous fluids in the form of either isotonic solution or hypotonic solution for at least 24 hours

Exclusion criteria

Exclusion criteria: abnormally high serum Na levels before joining the study (Na > 145 mg/dL) and without follow-up laboratory results before and after receiving intravenous fluids and had underlying disease such as heart failure, acute kidney injury, chronic kidney disease, nephritis, nephrotic syndrome and received diuretic drugs before or during the study

Design outcomes

Primary

MeasureTime frame
Risk of hypernatremia 24 hours Serum sodium

Secondary

MeasureTime frame
complication drowsiness seizure 24 hours GCS score

Countries

Thailand

Contacts

Public ContactManasjitt Boonyatarp

Lampang hospital

wkmanasjitt@gmail.com0869555532

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026