Monophasic neuromyelitis Optica relapses Neuromyelitis Optica Neuromyelitis optica spectrum Optic Neuritis Magnetic Resonance Imaging anti-aquaporin 4 autoantibody
Conditions
Interventions
Relapses NMOSD predefined as 1 relapse with in 6 months or 2 relapses within 12 months after stable maintenance treatment.,Monophasic NMOSD predefined as no relapse after stable of maintenance treatme
Diagnostic,Diagnostic
Relapses group,Non relapse group
Sponsors
Rajavithi Hospital, Rangsit University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Patients diagnosed with NMOSD by a neurologist according to IPND, 2015 diagnostic criteria. 2) The patient has undergone a magnetic resonance imaging (MRI) scan and has the images in the hospital's PAC system.
Exclusion criteria
Exclusion criteria: 1) The follow-up period less than 6 months. 2) Patients with other central nervous system pathologies such as cerebrovascular disease, neurological diseases, and cranial nerve disease. 3) Patients who refuse immunosuppressive treatment prescribed by a neurologists. 4) Incomplete data, or low quality MRI.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MRI features Within 6 months after stable treatment. Any MRI feature that have predictive value on relapses Neuromyelitis Optica. | — |
Secondary
| Measure | Time frame |
|---|---|
| Annualized relapse rate (ARR) Within 6 months after stable treatment. Relapses frequency divided by person-time in year.,Relapse NMOSD Within 6 months after stable treatment. Diagnosed by neurologist based on sudden onset of worsening symptom of central nervous system that persisted for morethan 24 hrs, without other explanation causes. | — |
Countries
Thailand
Contacts
Public ContactParinee Kemchoknatee
Rajavithi Hospital, Rangsit University
Outcome results
None listed