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Inflammatory markers in prior loop electrosurgical excision procedure (LEEP)as a prognosis factor in the recurrence of cervical intraepithelial neoplasia

Inflammatory markers in prior LEEP procedure as a prognosis factor in the recurrence of CIN

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20231120002
Enrollment
110
Registered
2023-11-20
Start date
2016-01-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

There are various studies demonstrating the relationship between inflammation and development of various solid cancers, including gynecological cancer. It is believed that oncological outcomes can be predicted through this concept (Chun et al., 2017

Interventions

Participants who had Recurrence CIN within 2 years after LEEP,Participants who had non-Recurrence CIN within 2 years after LEEP
Prevention,Prevention
Recurrence CIN,Non-Recurrence CIN

Sponsors

Department of Obstetrics and Gynecology, Faculty of Medicine, Bhumibol Adulyadej Hospital, Bangkok, Thailand
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Data was collected from medical records of patients from year 2016 to 2021. Inclusion criteria were patients who underwent LEEP of all CIN types with pathologic confirmation with followed up visits up to two years (at 6 months, 1 and 2 years). Preoperative hematological values were obtained within one month prior of LEEP procedure including CBC to calculate as systemic inflammatory values. NLR, PLR and MLR, SIRI, SII, and AISI

Exclusion criteria

Exclusion criteria: The exclusion criteria were incomplete data collection, loss or incomplete follow up, underwent hysterectomy due to no free margin and cervical cancer followed by LEEP procedure.

Design outcomes

Primary

MeasureTime frame
Recurrence CIN within 2 years after LEEP mean

Secondary

MeasureTime frame
Cut off values of inflammatory markers within 2 years after LEEP mean

Countries

Thailand

Contacts

Public ContactSamornrat Bunpreenant

Bhumibol Adulyadej Hospital, Bangkok, Thailand

bow.samornrat@gmail.com0992701215

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026