Comparison of the visual clarity between intravenous tranexamic acid and epinephrine-diluted irrigation during arthroscopic rotator cuff repair

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20231116001

Enrollment

Registered

2023-11-16

Start date

2024-03-18

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rotator cuff tears are indicated with shoulder arthroscopic repair Rotator cuff tear

Interventions

Patients with the tranexamic acid group will be injected intravenously 15 mg/kg tranexamic acid for 15 minutes with a slow speed of lower than 100 mg/minute before surgery, and the surgical shoulder w

Experimental Drug,Active Comparator Drug

intravenous tranexamic acid,Epinephrine-diluted irrigation

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with rotator cuff tears At least 18 years old

Exclusion criteria

Exclusion criteria: Irreparable rotator cuff tear Mental disability Pregnancy Uncontrolled hypertension History of allergic to tranexamic acid or epinephrine Previous venous thromboembolism History of stroke or cardiovascular diseases contraindicated with general anesthesia Known coagulopathy Required continuous anticoagulation or antiplatelet therapy History of renal or liver failure

Design outcomes

Primary

Measure	Time frame
Visual clarity of arthroscopic field After surgery Dense169 model evaluates visual clarity,Surgeon's perception of visual clarity After surgery Numeric rating scale from 0-10	—

Secondary

Measure	Time frame
Total operation time After surgery hours,Total irrigation fluid volume After surgery litters,Heart rates During surgery bpm,Blood pressure During surgery mmHg,Adverse events During surgery frequency,Postoperative pain On the first postoperative day VAS (visual analog scale),Postoperative swelling On the preoperative day and the first postoperative day cm/axillary circumference change,Pump pressure during surgery mmHg,The increase in pump pressure during surgery yes/no,Additional morphine use 1st postoperative day dose and mg,Number of times using radiofrequency device for hemostasis during surgery count	—

Measure

Time frame

Total operation time After surgery hours,Total irrigation fluid volume After surgery litters,Heart rates During surgery bpm,Blood pressure During surgery mmHg,Adverse events During surgery frequency,Postoperative pain On the first postoperative day VAS (visual analog scale),Postoperative swelling On the preoperative day and the first postoperative day cm/axillary circumference change,Pump pressure during surgery mmHg,The increase in pump pressure during surgery yes/no,Additional morphine use 1st postoperative day dose and mg,Number of times using radiofrequency device for hemostasis during surgery count

—

Countries

Thailand

Contacts

Public ContactSon Tran

Faculty of Medicine, Chulalongkorn University

tqson@ctump.edu.vn0966727480

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026