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3% Hypertonic Saline in Transforaminal Epidural Steroid Injection

Comparative-Effectiveness Study Evaluating Outcomes for Transforaminal Epidural Steroid Injections Performed with 3% Hypertonic Saline or Normal Saline in Lumbosacral Radicular Pain

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20231110006
Enrollment
245
Registered
2023-11-10
Start date
2014-07-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Transforaminal epidural steroid injection in patients with lumbosacral radicular pain. epidural steroid injection, herniated disc, hypertonic saline, lumbosacral radicular pain, post laminectomy pain, spinal stenosis, spondylolisthesis.

Interventions

The mixing of 0.9% NaCl to bupivacaine and triamcinolone for transforaminal epidural steroid injection,The mixing of 3% NaCl to bupivacaine and triamcinolone for transforaminal epidural steroid inject
Active Comparator Drug,Experimental Drug
Normal saline group (N group),Hypertonic saline group (H group)

Sponsors

Phramongkutklao Hospital and College of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients with a history of lumbosacral radicular pain more than 3 months, no effective response to pain medication or physiotherapy.

Exclusion criteria

Exclusion criteria: Incomplete medical records or loss of follow-up within 3 months fashion technique.

Design outcomes

Primary

MeasureTime frame
Pain score At 3 months follow up period The proportion of patients who achieved at least a 30% reduction in their 0-100 VRS leg pain score

Secondary

MeasureTime frame
Functional improvement At 1,3 and 6-months follow up period The proportion of patients who improved by at least 15% from baseline on the ODI at different follow-up periods , reduction in VRS leg pain and ODI scores, and serious side effects

Countries

Thailand

Contacts

Public ContactSithapan Munjupong

Phramongkutklao Hospital and College of Medicine

sithapan@gmail.com0991959255

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026