Alteration in Menstruation, sexuality and hormonal profile in reproductive woman with obesity after the bariatric surgery comparing before surgery. Bariatric surgery Menstruation Obesity Hormonal profile Reproductive woman Sexuality
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Reproductive aged women, aged 18-45 years, with obesity, who fulfilled the criteria for gastric sleeve resection (GSR), were considered eligible. 2. Thai ethnicity
Exclusion criteria
Exclusion criteria: 1. Other (non-PCOS) endocrine causes of ovarian dysfunction: - Thyroid dysfunction without treatment and thyroid hormone is out of normal range - Hyperprolactinemia without treatment and prolactin is out of normal range - Dysfunction of hypothalamus or pituitary gland - Failure of ovarian function such as premature ovarian insufficiency or ovarian dysgenesis 2. Structural abnormalities of genitalia: - Outflow tract obstruction - Mullerian dysgenesis 3. Previous surgery of bilateral oophorectomy or hysterectomy 4. Current or history of chemotherapy or radiation on brain or pelvic region 5. History of hormonal treatment during 3 months (combined contraceptive (pills/injection), progestin (pills/injection/implants/intrauterine system), Gonadotropins-releasing hormone (GnRH) agonist, Aromatase inhibitors, Tamoxifen, etc.) before bariatrics surgery 6. Pregnancy on the date of surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine the changing of menstrual patterns during 12 months after bariatric surgery comparing to before surgery. 12 month Questionaire and Menstrual record | — |
Secondary
| Measure | Time frame |
|---|---|
| The Changing of hormone profile during 12 months after bariatric surgery comparing to before surgery. 12 months Blood sampling for hormonal test,The changing of the Female Sexual Function Index (FSFI) during 12 months after bariatric surgery comparing to before surgery. 12 months Questionaire | — |
Countries
Thailand
Contacts
Faculty of Medicine, Prince of Songkla university