Overweight Obesity obesity overweight weight loss weight reduction
Conditions
Interventions
Intensive lifestyle intervention with meal replacement for 12 weeks,dietary advice and exercise advice for 150 minutes/weeks
Experimental Behavioral,No Intervention No treatment
Intensive lifestyle intervention with meal replacement,dietary advice
Sponsors
Prince of Songkla University
National Innovation Agency (Public Organization)
Eligibility
Sex/Gender
All
Age
20 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. age 20 years and above 2. body mass index > 23 kg/m2, without any weight change in 6 months (change <5%)
Exclusion criteria
Exclusion criteria: 1. pregnancy or lactation 2. diagnosis of myocardial infarction within the last 6 months 3. being on medication for chronic diseases e.g., anti-diabetic, anti-HT 4. Chronic kidney diseases: GFR <60 (ml/min/1.73 m2) 5. Diagnosis of liver cirrhosis, thyroid dysfunction, cancer of any organs 6. Diagnosis of GI tract diseases that compromises digestion or absorption of nutrients 7. on medication as follow: GLP-1 RA, SGLT2i, orlistat, TZD, insulin, sulfonylurea, topiramate, antipsychotics, antidepressant, SSRI, Phentermine 8. Drug abuse 9. Diagnosis of schizophrenia, major depressive disorder, bipolar disorder, eating disorder 10. actively participate in other clinical trials
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| body weight at 12, and 24 weeks after an end of intervention kilograms | — |
Secondary
| Measure | Time frame |
|---|---|
| body composition (fat mass, muscle mass) at 12, and 24 weeks after an end of intervention kilograms | — |
Countries
Thailand
Contacts
Public ContactSupattra Uppanisakorn
Faculty of Medicine, Prince of Songkla University
Outcome results
None listed