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Investigating neural mechanisms of age-related decline in attention and memory functions and developing transcranial brain stimulation protocols for mild cognitive impairment

Investigating neural mechanisms of age-related decline in attention and memory functions and developing transcranial brain stimulation protocols for mild cognitive impairment

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
TCTR
Registry ID
TCTR20231102002
Enrollment
720
Registered
2023-11-02
Start date
2024-01-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild Cognitive Impairment (MCI) Mild Cognitive Impairment MCI

Interventions

This process will be repeated for a total of 4 days, with each day involving stimulation in different positions: (1) left parietal, (2) right parietal, (3) frontal, and (4) sham stimulation. The order
Experimental Device,Experimental Device,Experimental Device,Sham Comparator Device
medial-frontal cortex,left parietal cortex,right parietal,Sham

Sponsors

National Research Council of Thailand
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Thai nationality. Normal vision and hearing, or corrected to normal. For healthy elderly individuals with a MoCA score of 25 or more points. For individuals with Mild Cognitive Impairment (MCI) with a MoCA score of fewer than 25 points.

Exclusion criteria

Exclusion criteria: Temporary confusion due to delirium. Underlying brain conditions such as epilepsy or stroke. A history of treated psychiatric disorders. A history of head injuries resulting in loss of consciousness. Inability to use a keyboard or mouse to control a computer. No other chronic illnesses like diabetes or heart disease. Mobility issues preventing normal physical activity.

Design outcomes

Primary

MeasureTime frame
Behavior Before and after intervention Hit rate,EEG Before and after intervention ERP

Secondary

MeasureTime frame
N/A N/A N/A

Countries

Thailand

Contacts

Public ContactChaipat Chunharas

King Chulalongkorn Memorial Hospital

Chaipat.c@chula.ac.th022564000

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026