the prevalence of hyperprolactinemia and identify the factors associated with its occurrence in patients diagnosed with major depressive disorder. Hyperprolactinemia, depression, prevalence, association factors
Conditions
Interventions
Plasma prolactin levels less than 25 ng/ml in female and less than 20 ng/ml in male,blood prolactin levels exceeding 25 ng/mL in females and 20 ng/mL in males
Screening,Screening
Normal prolactin levels,Hyperprolactinemia
Sponsors
Faculty of medicine, Chulalongkorn university
Eligibility
Sex/Gender
All
Age
16 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Age between 18 to 60 years old 2. Diagnosed as depression according to ICD-10 criteria
Exclusion criteria
Exclusion criteria: 1. CKD stage III-V 2. Primary hyperparathyroidism 3. Granulomatous disease 4. GI malabsorption: short bowel syndrome, pancreatitis, IBD, bariatric surgery 5. Liver disease 6. Renal insufficiency and nephrotic syndrome 7. History of drug use in one year: anticonvulsants, antifungal, anti-inflammatory agents, Antiretroviral drugs (Ritonavir) Pregnancy and lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The prevalence of hyperprolactinemia in MDD patients At time of visit and evaluate severity of depression plasma prolactin levels | — |
Secondary
| Measure | Time frame |
|---|---|
| association factors of Hyperprolactinemia At time of visit questionnaire and medical records | — |
Countries
Thailand
Contacts
Public ContactJirawan Pongrujikorn
Vachiraphuket hospital
Outcome results
None listed