Postoperative pain following spinal fusion surgery can lead to a series of significant complications local and intravenous ketorolac, postoperative pain, lumbar spinal fusion
Conditions
Interventions
standard analgesic
Marcaine 10ml mixed with normal saline upto 20ml locally injection,intravenous ketorolac 30 mg immediate post op and Marcaine 10ml mixed with normal saline upto 20ml locally inject
Experimental Drug,Experimental Drug,Experimental Drug
standard analgesic,intravenous ketorolac,local ketorolac
Sponsors
Institutional Review Board Royal Thai Army Medical Department
Eligibility
Sex/Gender
All
Age
20 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Ages of 20 and 75 2. undergoing lumbar spinal fusion between 1-3 levels 3. no history of long-term opioid use 4. Patients who are ASA classification 1-3
Exclusion criteria
Exclusion criteria: 1.Ongoing infection 2.History of cancer 3.Allergic to ketorolac or analgesia 4.Smoking 5.Contraindication for NSAIDs : chronic kidney disease(GFR<60 ml/min/1.73m2) 6.Patients who had history of GI bleeding and gastritis 7.Previous back surgery 8.Unwilling to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative morphine consumption per day (administered using a patient-controlled analgesia pump) postoperative day0-3 Postoperative morphine consumption per hous | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain score at specific hours after the operation postoperative until discharge visual analog scale (VAS),Satisfaction postoperative until discharge Questionaire,Drain output postoperative until drain removed ml. per day,Length of stay postoperative until discharge day,renal side effect postoperative day1 creatinine clearance on postoperative day1,Fusion rate at 1 year (by CT scan) at 12 months after intervention CT scan | — |
Countries
Thailand
Contacts
Public ContactRatchanon Buakhwan
Phramongkutklao Hospital
Outcome results
None listed