Patient with atopic dermatitis antiallergic agent antimicrobial activity Lumbricus rubellus atopic dermatitis IL-31
Conditions
Interventions
Patients caregivers were asked to fill out a questionnaire about the patients identity and history of AD, atopy, asthma, allergic rhinitis, previous or ongoing medications, and other diseases. The cli
Intervention Group
Sponsors
Universitas Syiah Kuala (The Ministry of Education, Culture, Research and Technology)
Eligibility
Sex/Gender
All
Age
8 Years to 16 Years
Inclusion criteria
Inclusion criteria: (1) AD patients with Scoring Atopic Dermatitis (SCORAD) index > 25 and meeting the Hanifin and Rajka criteria, (2) aged 8-16 years old, (3) total serum IgE level >100 IU/mL, (4) healthy weight (5th-85th percentile) children based on the CDC BMI-for-age (2-20 years old) growth chart
Exclusion criteria
Exclusion criteria: 1) treated with steroid, systemic antihistamine, or phototherapy in the last month and systemic immunosuppressive therapy in the last three months, (2) obtained systemic antibiotic in the last one month, (3) used topical antibiotic or antiseptic soap in the last two weeks, (4) had immunosuppressive or systemic diseases, and (5) positive feces identification for intestinal nematode parasites (e.g., Ascaris lumbricoides, Enterobius vermicularis)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Staphylococcus aureus colonization The patients were evaluated after fourteen days. catalase test, coagulase test, and MSA media | — |
Secondary
| Measure | Time frame |
|---|---|
| IL-31 levels The patients were evaluated after fourteen days. ELISA assay | — |
Countries
Indonesia
Contacts
Public ContactMeutia Sara
Faculty of Medicine, Universitas Syiah Kuala, Indonesia
Outcome results
None listed