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The effects of moderate-intensity aerobic exercise interventions in people with IgA nephropathy: a Randomized Controlled Trial

The effects of moderate-intensity aerobic exercise in people with IgA nephropathy:a randomized controlled trial

Status
Unknown
Phases
Early Phase 1
Study type
Interventional
Source
TCTR
Registry ID
TCTR20231019003
Enrollment
70
Registered
2023-10-19
Start date
2023-10-31
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

IgA nephropathy physical activity IgA nephropathy physical activity

Interventions

Participants in this group were required to undergo home personalized exercise training monitored by a wristband under the guidance of a physician for 12 months 4 times a week. ,Patients in this group
Experimental Other,No Intervention Other
PA,CTL

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 65 Years

Inclusion criteria

Inclusion criteria: IgAN confirmed by renal biopsy; Age over 16 years old, regardless of gender; Patients with eGFR over 15ml/min/1.73m; Irregular exercise habits in the last year.

Exclusion criteria

Exclusion criteria: 1.Other autoimmune diseases or secondary kidney diseases, such assystemic lupus erythematosus, systemic sclerosis, rheumatoid arthritis, diabetic nephropathy, cirrhosis, nephrotoxic drugs, etc. 2.Those on dialysis or those who are expected to be on dialysis within 1 year; 3.Suffering from other critical diseases such as heart failure, respiratory failure, malignant tumor, severe infection, severe trauma, mental disorders, severe dementia, etc. 4.Patients who underwent or required hormonal and/or immunosuppressant therapy within 6 months prior to this study were included; 5.Patients who cannot be followed up regularly; 6.Patients with musculoskeletal lesions; 7.pregnant or lactating women.

Design outcomes

Primary

MeasureTime frame
Serum creatinine at 12 months after end of the intervention Blood biochemical tests,proteinuria at 12 months after end of the intervention Urine tests

Secondary

MeasureTime frame
Exercise tolerance at 12 months after end of the intervention 6 minutes walk test,Upper extremity strength at 12 months after end of the intervention hand grip,Lower extremity muscle strength at 12 months after end of the intervention sit to stand test,weight at 12 months after end of the intervention Scales,Quality of life at 12 months after end of the intervention SF-36

Countries

China

Contacts

Public ContactDandan Yang

West China Hospital of Sichuan University

yangdandanmedical@163.com13258133761

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026