efficacy of Ibuprofen and paracetamol in reducing pain after endometrial biopsy in abnormal uterine bleeding women at gynecologic-outpatient department of sunprasitthiprasong hospital

Efficacy of Ibuprofen and Paracetamol in reducing pain after endometrial biopsy in abnormal uterine bleeding women at Gynecologic-outpatient department of Sunprasitthiprasong hospital

Status

Unknown

Phases

Phase 2

Study type

Interventional

Source

TCTR

Registry ID

TCTR20231017005

Enrollment

Registered

2023-10-17

Start date

2023-07-24

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

All women who have abnormal uterine bleeding Abnormal uterine bleeding

Interventions

Ibuprofen (400mg) 1 tab po 30 min before the procedure,Paracetamol (500 mg)1 tab po 30 min before the procedure

Experimental Drug,Active Comparator Drug

Ibuprofen,Paracetamol

Eligibility

Sex/Gender

Female

Age

35 Years to No maximum

Inclusion criteria

Inclusion criteria: Abnormal uterine bleeding women with 1. age more than 35 years old or 2.risk for anovulation (PCOS, BMI more than 25 kg/m2, abnormal ultrasound finding) or 3. medical failure treatment or 4.risk of endometrial cancer (Tamoxifen using, Lynch syndrome, family history of colon or cervical cancer)

Exclusion criteria

Exclusion criteria: 1. do not consent to participate 2. pregnancy 3. History of allergy or suspected allergy of Paracetamol or Ibuprofen 4. Asthma, GI bleeding, liver disease, renal disease, cardiovascular disease

Design outcomes

Primary

Measure	Time frame
pain score at 30 minutes after the procedure 30 minutes after the procedure Numeric rating scale	—

Secondary

Measure	Time frame
pain score during the procedure 30 minutes after the procedure Numeric rating scale,pain score at immediately after the procedure immediately after the procedure Numeric rating scale,pain score at 60 minutes after the procedure 60 minutes after the procedure Numeric rating scale,satisfactation 30 minutes after the procedure less, intermediate, very statisfied	—

Countries

Thailand

Contacts

Public ContactRattiyakorn Lertdee

Sunprasitthiprasong Hospital

meenlpf@gmail.com0819481297

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026