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The Evaluation of Pain and Wound Healing in Patients with Alveolitis Treated with A-PRF (Advanced Platelet-Rich Fibrin), Photobiomodulation, Pentoxifylline, and Alveogyl Applications

The Evaluation of Pain and Wound Healing in Patients with Alveolitis Treated with A-PRF (Advanced Platelet-Rich Fibrin), Photobiomodulation, Pentoxifylline, and Alveogyl Applications

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20231014003
Enrollment
91
Registered
2023-10-14
Start date
2022-10-12
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alveolar osteitis Alveolar Osteitis, Photobiomodulation Therapy, Pentoxifylline, A-PRF

Interventions

Irrigation was performed with saline solution, and Alveogyl was placed.,Following irrigation with saline solution, photobiomodulation was performed intraorally on the occlusal and buccal regions (on p
s blood was collected into a plastic tube without anticoagulant, and it was centrifuged at 1500 rpm for 14 minutes to obtain Advanced Platelet-Rich Fibrin (A-PRF). A-PRF was placed in the tooth extrac
Saline+ Alveogyl,Saline+ Photobiomodulation,Saline+ A-PRF,Saline+ Pentoxyfilline

Sponsors

Faculty of Dentistry
Lead Sponsor
No Study Secondary Sponsor
Collaborator

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients aged 18-65 years, Cases of alveolitis developed on days 3-5 after tooth extraction, Patients who have not received alveolitis treatment, Patients without systemic illness, Patients who do not exhibit signs of active infection around the tooth extraction socket

Exclusion criteria

Exclusion criteria: Patients under 18 and over 65 years of age, Patients with systemic illness, Patients with active infection in the tooth extraction socket area, Patients who have received alveolitis treatment, Patients using oral contraceptives, Pregnant patients, Breastfeeding patients, Patients who use tobacco and alcohol, Patients unable to provide informed consent in person, Patients with incomplete examination and control records

Design outcomes

Primary

MeasureTime frame
Pain Postoperative 0,2,4 and 7th days VAS (Visual Analog Scale)

Secondary

MeasureTime frame
Wound Healing Postoperative 0,1 and 2nd weeks Landry Indeks

Countries

Turkey

Contacts

Public ContactNeslihan Eroglu

Akdeniz University

neslihanakca2003@yahoo.com05326084485

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026