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The association of relative dose-intensity of Platinum-based doublet chemotherapy and the survival outcome in Advanced stage Non-small cell lung cancer

The association of relative dose-intensity of Platinum-based doublet chemotherapy and the survival outcome in Advanced stage Non-small cell lung cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20231012010
Enrollment
250
Registered
2023-10-12
Start date
2023-02-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-small cell lung cancer Receiving Chemotherapy Non-small cell lung cancer Chemotherapy, Platinum-based Dosage Intensity Progression-Free Survival Retrospective Cohort Studies Kaplan-Meier Estimate Cox Proportional Hazards Models Thailand

Interventions

NSCLC who receive platinum-based chemotherapy as a first-line treatment.
Treatment
Overall NSCLC

Sponsors

Department of Medicine, Maharat Nakhon Ratchasima Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients of both sexes over 18 years old who were diagnosed with advanced-stage non-small cell lung cancer were included. As the first-line treatment, platinum-containing chemotherapy was required for all patients. ECOG Performance must be between 0 and 2.

Exclusion criteria

Exclusion criteria: Patients having previous malignancies in the preceding five years, excluding basal cell carcinoma and other localized skin cancers, were excluded from the study. Other exclusion criteria comprised patients with platinum-containing chemotherapy during the preceding 12 months or those with uncontrolled brain metastases.

Design outcomes

Primary

MeasureTime frame
Progression-free survival SoC CT schedule, Death RECIST Version 1.1

Secondary

MeasureTime frame
Overall survival Death Death status, Date of Death or Date of Last Follow up in Loss F/U case,Overall response rate SoC CT schedule RECIST Version 1.1,Interested Adverse Event SoC visit schedule CTCAE v. 5

Countries

Thailand

Contacts

Public ContactJirawat Thanestada

Maharat Nakhon Ratchasima hospital

jthanestada@gmail.com044235870

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026