Facial wrinkle in the nasolabial folds area skin aging, nasolabial fold, rejuvenation, microneedle patch, microneedling
Conditions
Interventions
The microneedle (MN) array was fabricated on the fabric substrate via the photo-polymerization technique. Each microneedle was designed with a pyramidal shape. The average height (h) of microneedles i
Active Comparator Device,Active Comparator Device
Microneedle patch,Microneedle patch
Sponsors
Thammasat University
Eligibility
Sex/Gender
Female
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Female patient age between 20-60 years old 2. Mild to moderate nasolabial folds according to the Merz Aesthetics Scale
Exclusion criteria
Exclusion criteria: 1. Patient refuses to participate in the study 2. Pregnancy or lactation 3. History of energy base device treatment within 1 year 4. History of laser therapy within 6 months 5. History of chemical peeling within 1 month 6. History of mesotherapy injection at nasolabial folds within 1 month 7. History of Botox or filler injection at nasolabial folds within 1 year 8. History of taking antiplatelet and anticoagulants within 1 month 9. A current or prior history of infectious skin disease 10. A current or prior history of eczematous dermatitis on the face 11. A current or prior history of using immunosuppressive therapy 12. A current or prior history of allergy or hypersensitivity to polymethylmethacrylate (PMMA) and the monomer plastic 13. A current or prior history of collagen supplement 14. Other underlying that cosmetic affect their health condition
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of Nasolabial folds at 2 weeks interval for a total of 12 weeks Merz Aesthetics Scale | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain score At 2 weeks interval for a total of 12 weeks visual analog scale ,Skin elasticity At 2 weeks interval for a total of 12 weeks Cutometer,Skin roughness At 2 weeks interval for a total of 12 weeks Antera 3D,Participants satisfaction At 2 weeks interval for a total of 12 weeks Participants satisfaction score | — |
Countries
Thailand
Contacts
Public ContactJitlada Meephansan
Chulabhorn International College of Medicine, Thammasat University
Outcome results
None listed