lip hyperpigmentation Lip
Conditions
Interventions
picosecond laser 1064-nm (enlighten) spot size 6-8 mm, fluence 0.4-0.6 J/cm2, 2-3 Hz, 2-3 pass, every 2 weeks total 6 sessions
Experimental Procedure/Surgery
Picosecond laser 1064-nm
Sponsors
Institute of Dermatology
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Lip hyperpigmentation characterized by bilateral hyperpigmented patch on upper and/or lower lip
Exclusion criteria
Exclusion criteria: 1. Lip hyperpigmentation from disease such as lichen planus, lupus erythematosus, pemphigus, pemphigoid, fixed drug eruptions, pigmented contact cheilitis, orofacial granulomatosis, ephelides, labial melanotic macule, acquired dermal melanocytosis, melanoacanthoma, lentigines, nevus, malignant melanoma, pigmented Bowen disease, squamous cell carcinoma, melanoma, actinic cheilitis, Lentiginosis syndromes, Addison disease, Cushing disease, Nelson syndrome, acromegaly, hyperthyroidism, and hemochromatosis which diagnose by history taking and physical examination 2. History of procedures at lip such as tattoo, filler injection or laser 3. History of keloid or hypertrophic scar 4. History of labial herpes infection 5. Infection at lip 6. Pregnancy or breast feeding 7. History of smoking 8. History of drugs such as minocycline, zidovudine, cyclophosphamide, doxorubicin, escitalopram, levodopa, nicotine and tacrolimus
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Melanin index at 6 months after end of the laser Mexameter | — |
Secondary
| Measure | Time frame |
|---|---|
| Physician assessment at 6 months after end of the laser Physician assess percentages of improvement of lip hyperpigmentation,Patient satisfaction at 6 months after end of the laser Patient reported outcome using a customer satisfaction scores | — |
Countries
Thailand
Contacts
Public ContactPichanun Sangchaisirisak
Institute of Dermatology
Outcome results
None listed