Male and female healthy subjects Cordyceps militaris, Healthy subjects, NK cell, Cytokine, Immunomodulation
Conditions
Interventions
Male received single oral dose of functional beverages from submerged fermentation of Cordyceps militaris (FCM),Male received placebo,Female received single oral dose of functional beverages from subm
MFCM,MPB,FFCM,FPB
Sponsors
National Innovation Agency (NIA)
Eligibility
Sex/Gender
All
Age
25 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1) Male and female adult participants aged 25-60 during the screening test. 2) No history of hypersensitivity or idiosyncratic reactions to drugs or herbal products. 3) Willing to participate in the project throughout the research program.
Exclusion criteria
Exclusion criteria: 1) Participants diagnosed with immune-mediated disease, nervous system disorders, cardiovascular disease, or liver or kidney disease. 2) Participants diagnosed with chronic health problems such as hypertension, diabetes, or renal failure, etc. 3) A body mass index (BMI) greater than 29.9 or less than 18 kg/m2. 4) Participants who were pregnant or lactating or intended to become pregnant during the trial period. 5) Participants who, within two weeks, ingested a drug or functional food that may affect the immunomodulatory effect of the test product 6) Participants who had an alanine transaminase (ALT) or aspartate transaminase (AST) plasma level more than three times the guideline of the organization.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Immune Response at 4 and 8 weeks after end of the intervention T cell absolute count, B cell absolute count, Natural Killer (NK) cell absolute count, and Cytokine levels | — |
Secondary
| Measure | Time frame |
|---|---|
| Safety at 4 and 8 weeks after end of the intervention Hematological, metabolic, and safety indexes | — |
Countries
Thailand
Contacts
Public ContactAtcharaporn Ontawong
University of Phayao
Outcome results
None listed