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A Split-Face Comparison of Novel Microneedle Patch versus Botulinum Toxin-A and Microneedle Patch for Improvement in Undereye Skin Texture

A Split-Face Comparison of Novel Microneedle Patch versus Botulinum Toxin-A and Microneedle Patch for Improvement in Undereye Skin Texture

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20231002007
Enrollment
25
Registered
2023-10-02
Start date
2022-09-22
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy population microneedle patch, transdermal drug delivery, wrinkle, botulinum toxin

Interventions

new design microneedle patch for botulinum toxin delivery
Active Comparator Device

Sponsors

Thammasat University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
25 Years to 40 Years

Inclusion criteria

Inclusion criteria: Patients' consent was also obtained prior to the use of the images for medical purposes. Based on the Scientific Assessment Scale of Skin Quality (SASSQ) and Merz infraorbital hollow rating scale, all participants presented moderate to severe skin texture

Exclusion criteria

Exclusion criteria: there was a history of filler use within one year of study enrollment; the use of botulinum toxin injection in the previous six months; use of laser therapy in the previous six months of laser therapy; a history of light or radiofrequency use to the face; or the use of chemical peel within three months of study recruitment. Volunteers with existing infectious skin disease or eczematous dermatitis, those taking immunosuppressive therapy, women with hypersensitivity or allergy to cosmetics, those using a topical anti-wrinkle regimen for at least three months prior to recruitment, and pregnant or lactating women were also excluded from participating in the study.

Design outcomes

Primary

MeasureTime frame
SASSQ skin quality rating scale 16 weeks photo

Secondary

MeasureTime frame
Merz infraorbital hollow scale 16 weeks photo

Countries

Thailand

Contacts

Public ContactJITLADA Meephansan

Chulabhorn International College of Medicine, Thammasat University

kae_mdcu@yahoo.com0972468497

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026