Healthy population microneedle patch, transdermal drug delivery, wrinkle, botulinum toxin
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients' consent was also obtained prior to the use of the images for medical purposes. Based on the Scientific Assessment Scale of Skin Quality (SASSQ) and Merz infraorbital hollow rating scale, all participants presented moderate to severe skin texture
Exclusion criteria
Exclusion criteria: there was a history of filler use within one year of study enrollment; the use of botulinum toxin injection in the previous six months; use of laser therapy in the previous six months of laser therapy; a history of light or radiofrequency use to the face; or the use of chemical peel within three months of study recruitment. Volunteers with existing infectious skin disease or eczematous dermatitis, those taking immunosuppressive therapy, women with hypersensitivity or allergy to cosmetics, those using a topical anti-wrinkle regimen for at least three months prior to recruitment, and pregnant or lactating women were also excluded from participating in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SASSQ skin quality rating scale 16 weeks photo | — |
Secondary
| Measure | Time frame |
|---|---|
| Merz infraorbital hollow scale 16 weeks photo | — |
Countries
Thailand
Contacts
Chulabhorn International College of Medicine, Thammasat University