Efficacy of Add-on Hemoperfusion in Hospitalized Patients with Severe to Critical COVID-19 Disease

Efficacy of Hemoperfusion in COVID-19 Disease : single tertiary-center retrospective observational study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

TCTR

Registry ID

TCTR20231002006

Enrollment

300

Registered

2023-10-02

Start date

2020-01-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyperinflammatory state in coronavirus disease 2019 (COVID-19). coronavirus disease 2019, hemoperfusion, blood purification, cytokine, HA-330, mortality

Interventions

Patients receive an add-on HP with a cytokine adsorbent treatment in addition to the standard treatment,Patients receive standard treatment following guidelines for critically ill patients with COVID-

Treatment,Treatment

Add-on HP with a cytokine adsorbent treatment,Standard medical treatment

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1.Age 18 years and over, 2. Confirmed SARS-CoV-2 infection through reverse transcriptase polymerase chain reaction (PCR) testing, 3. Classified as having severe to critical COVID-19 disease according to the World health Organization (WHO) classification

Exclusion criteria

Exclusion criteria: 1. Comorbidities associated with a life expectancy of less than 6 months, 2.Uncontrolled bleeding, 3. Moribund conditions with an expected imminent death within 24 hours.

Design outcomes

Primary

Measure	Time frame
hospital mortality hospital discharge retrospective chart review	—

Secondary

Measure	Time frame
14-day mortality hospital discharge retrospective chart review,28-day mortality hospital discharge retrospective chart review,90-day mortality hospital discharge retrospective chart review,ICU mortality hospital discharge retrospective chart review,ICU length of stays hospital discharge retrospective chart review,hospital length of stays hospital discharge retrospective chart review,ventilator day hospital discharge retrospective chart review	—

Measure

Time frame

14-day mortality hospital discharge retrospective chart review,28-day mortality hospital discharge retrospective chart review,90-day mortality hospital discharge retrospective chart review,ICU mortality hospital discharge retrospective chart review,ICU length of stays hospital discharge retrospective chart review,hospital length of stays hospital discharge retrospective chart review,ventilator day hospital discharge retrospective chart review

—

Countries

Thailand

Contacts

Public ContactSupattra Chiewroongroj

Faculty of Medicine Siriraj Hospital

supattra.c@nmu.ac.th024197000

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026