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Association between extractable protein levels in natural rubber latex gloves and latex sensitization among hospital personnel

Association between extractable protein levels in natural rubber latex gloves and latex sensitization among hospital personnel

Status
Unknown
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20230929006
Enrollment
680
Registered
2023-09-29
Start date
2023-12-04
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Latex sensitization Latex allergy Natural Rubber Latex Allergy

Interventions

Health personnel who use latex glove which extractable protein determined by the modified Lowry method is more than or equal 200 microgram per dm2.,Health personnel who use latex glove which extractab
High extractable protein latex gloves exposure group,Low extractable protein latex gloves exposure group,No major allergens latex gloves exposure group

Sponsors

Research Affairs
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Study population for high extractable protein latex gloves exposure group: health personnel who used high extractable protein latex gloves at work for at least six months, at least three pairs/day or at least 18 hours per week 2. Study population for low extractable protein and no major allergens latex gloves exposure group: nursing staff who used high extractable protein latex gloves at work for at least six months, at least three pairs/day

Exclusion criteria

Exclusion criteria: 1. Study population for high extractable protein latex gloves exposure group: health personnel who used latex gloves in their occupation not officially provided from the Khon Kaen Hospital, which must be done before recruiting participants by survey. 2. Study population for low extractable protein and no major allergens latex gloves exposure group: nursing staff who used latex gloves in their occupation not officially provided from the Faculty of Medicine, Khon Kaen university, which must be done before recruiting participants by survey.

Design outcomes

Primary

MeasureTime frame
Latex sensitization and no latex sensitization which are qualitative results immediately after taking serum from samples to analyze Serum latex specific IgE levels

Secondary

MeasureTime frame
Serum latex specific IgE levels which are quantitative results immediately after taking serum from samples to analyze Serum latex specific IgE levels

Countries

Thailand

Contacts

Public ContactChawapon Luengtongkam

Khon Kaen University

chawlu@kku.ac.th0877892971

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026