venous thromboembolism Deep vein thrombosis Pulmonary embolism critical illness venous thromboembolism Deep vein thrombosis Pulmonary embolism pharmacological thromboprophylaxis mechanical thromboprophylaxis
Conditions
Interventions
231 of volunteers, without thromboprophylaxis, who are routinely under surveillance and early ambulation ,231 of volunteers, with pharmacological or mechanical thromboprophylaxis as attending doctors
Prevention,Prevention
pre-implementation ,post-implementation
Sponsors
Faculty of Medicine, Chiang Mai University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. age over 18 year old 2. following indication a. admit in critical care unit b. at least 1 condition below i. respiratory failure, need for mechanical ventilator ii. Acute kidney injury impending to renal replacement therapy iii. sepsis which SOFA score over 2 (reference from The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) iv. hemodynamic unstable
Exclusion criteria
Exclusion criteria: 1. taken anticoagulant during study 2. history of thrombophilia 3. undergone major operation 3 months prior to study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VTE incidence of the pre-implementation period from admission to 45 days after discharge official doppler ultrasound by radiologist, CT pulmonary angiogram and other imaging modalities as clinical suggestion,VTE incidence of the post-implementation period from admission to 45 days after discharge official doppler ultrasound by radiologist, CT pulmonary angiogram and other imaging modalities as clinical suggestion,incidence of adverse event from thromboprophylaxis during admission observation, physical examination, Lab parameter | — |
Secondary
| Measure | Time frame |
|---|---|
| mechanical ventilation day from admission to 45 days after discharge observation,all cause mortality rate from admission to 45 days after discharge observe,Length of ICU stay from admission to discharge date observation | — |
Countries
Thailand
Contacts
Public ContactPeampost Sinsakolwat
Faculty of medicine, Chiang Mai university
Outcome results
None listed