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The feasibility of blood flow-restricted resistance exercise in individuals with chronic heart failure

The feasibility of blood flow-restricted resistance exercise in individuals with chronic heart failure

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20230927001
Enrollment
50
Registered
2023-09-27
Start date
2023-10-12
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with chronic heart failure Chronic Heart Failure, BFR, resistance exercise

Interventions

The subjects will perform squat exercises with high resistance.,The subjects will perform squat exercises with low resistance.,The subjects will perform squat exercises with low-resistance exercises c
Experimental Behavioral,Experimental Behavioral,Experimental Behavioral,Experimental Behavioral,Experimental Behavioral,Experimental Behavioral
High-resistance exercises,Low-resistance exercises,Low-resistance exercises combined with continuous low-resistance pressure exercises,Low-resistance exercises combined with intermittent low-resistanc

Sponsors

None
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients with chronic HF under stable clinical condition, aged over 20, can follow instructions without mental illness or hearing impairment.

Exclusion criteria

Exclusion criteria: 1. Have resistance training within the past six months. 2. Unable to perform squats due to degenerative joint arthritis. 3. Walk less than 30 minutes daily. 4. Have a history of venous thrombosis. 5. Peripheral neuropathy. 6. Severe peripheral arterial disease. 7. Impaired kidney function. 8. Severe hypertension. 9. Under dual antiplatelet therapy.

Design outcomes

Primary

MeasureTime frame
Hemodynamics Before, during, and after exercise blood pressure, heart rate, blood oxygen level,Perceived exertion Before, during exercise, and after exercise questionnaire,Indicators of muscle damage and coagulation factors Before, immediate after exercise, and recovery 20 minutes blood draw

Secondary

MeasureTime frame
Responses of local muscle During exercise Electromyography, and Near-infrared spectroscopy

Countries

Taiwan

Contacts

Public ContactChiaoNan Chen

National Yang Ming Chiao Tung university

chiaonanchen@gmail.com886228267000

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026